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Grain
Less
By Dr.
J. K. Tukra
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Some
folks cant stomach the gluten found in cereals. It may
be hurting their head as well.
There are some people, most of them of European ancestry,
for whom many grains are dangerous. Their body cant
tolerate a protein called gluten thats found in wheat,
rye and barley. For reasons that arent clear, their
immune system responds to the presence of gluten in the diet
by attacking the small intestine. Gluten sensitivity can lead
to severe malnutrition, and appears to increase the risk of
certain cancers.
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Now comes word that this condition, known
as celiac disease, may affect the brain as well. In a study
published in the journal Neurology, Dr. Marios Hadjivassiliou
and his colleagues at the Royal Hallamshire Hospital in Sheffield,
England, found that a wheat-free diet dramatically reduced the
number of debilitating headaches suffered by some of their gluten
sensitive patients. MRI brain scans suggest that gluten somehow
triggered an inflammatory response in the white matter of the
cerebrum. It was a small study, and it has yet to be reproduced.
But the Neurology report underscores an important point about
celiac disease: its symptoms can be unpredictable and may mimic
those of other disorders.
Fortunately, doctors have developed reliable tests to diagnose
the illness. The presence of several key antibodies in the blood
provides one important clue. The clincher is an endoscopic examination
of the small intestine that reveals damage wrecked by a runaway
immune system. Although celiac disease is a hereditary disorder,
it can strike at any time, starting in childhood. The
first peak occurs at one to three years of age, says Dr.
Marvin Ament, a pediatric gastroenterologist at UCLA. Typically,
within six months after the introduction of cereals [to an infants
diet], youll see a change in the stools. Theres
progressively more diarrhea, and youll notice that the
growth rate starts to slow. Other peaks occur just before
puberty and in the 40s.
Adults often exhibit a much wider range of symptoms. They may
or may not have diarrhea. Frequently they become anemic, because
their intestine cant absorb much iron. Complicating the
diagnosis is the fact that many symptoms of celiac disease are
seen in other illnesses, such as Crohns disease, ulcerative
colitis, diverticulosis or intestinal infections. If you are
found to suffer from gluten sensitivity, youll soon discover
that its difficult to adopt a gluten-free diet. The protein
is widely used as a thickener in soups, canned vegetables and
other processed foods and often contaminates products make with
oats. It also takes a while flour made from rice, soy or potatoes
(none of which contain gluten).
Whatever you do, dont assume that condition yourself.
We get calls all the time from people who have been gluten-free
for six months or a year and now wonder if they have celiac
disease, says Sue Goldstein, founder of the Westchester
Celiac Support Group in New York. By then, diagnosis is very
difficult; to telltale antibodies will have disappeared, and
the intestinal biopsy may not show anything wrong. You may even
have to re-expose yourself to wheat, and get sick again, to
prove that your gut instinct was right. |
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Hurting
Patients
suffering from fibromyalgia used to be told that it
was all in their. Not anymore
Fibromyalgia is a mysterious illness with a long name
and a bad reputation. For years, patients who went to
their doctors complaining of inexplicable pain, stiffness
and fatigue were told that they were depressed or stressed
out and their symptoms were psychosomatic. More recently,
fibromyalgia has been linked to chronic-fatigue syndrome
and the aftereffects of Lyme disease, which in some
medical circles in enough to give any ailment a bad
name.
But the reputation is undeserved. Fibromyalgia is a
real medical syndrome that is being taken more seriously
these days, thanks to a study out of the University
of Alabama that has found what may be the underlying
causes: a reduced blood flow to the parts of the brain
that process pain and twice the normal level of a brain
chemical called substance P, which helps nervous system
cells send pain messages to the brain. Not only do patients
now have scientific support to prove they are not crazy
but doctors also have more reason to take their complaints
seriously.
The complaints are serious indeed, from swelling, tingling,
numbness and stiffness in the soft tissues (muscles,
tendons and ligaments) to achy, throbbing pain that
is worse in the morning intensifies
again at night and has been known to drive suffers to
suicide. Fatigue is a common complaint (reported in
as many as 9 out of 10 cases), caused perhaps by disturbances
in the deep-sleep phase the body needs to get properly
refreshed at night. Patients have told me that they
feel so heavy in the morning they can hardly get out
of bed and that they often find it difficult to concentrate
on even minor tasks. For reasons that are not known,
women get fibromyalgia seven times as often as men,
but the ailment can strike anyone at any age.
Doctors are at a disadvantage in diagnosing fibromyalgia
because many of its symptoms are shared by other illnesses.
Compounding the problem is the fact that even with these
recent findings, there are still no definitive fibromyalgia
markers. X rays and blood tests can be used only to
rule out other illnesses. To facilitate diagnosis, the
American College of Rheumatology established a procedure
for examining 18 tender points on a patients body.
If the muscles feel very sore when pressed in 11 of
these 18 points, a tentative diagnosis of fibromyalgia
can be made.
Although there is no known cure, there are treatments
that work. In fact, many patients have managed the disease
successfully with a combination of simple exercises
as cycling and jogging. Though many patients say these
exercise only worsen the pain, working through the discomfort
can eventually bring relief. Tricyclic antidepressants
such as amitriptyline and cyclobenzaprine are sometimes
prescribed to improve sleep and relax muscles. Some
patients opt for temporary pain relief via local anesthetic
or steroid injections. There is no single regimen that
helps everyone. Just keep trying until you find one
that words. And dont let anyone tell you its
all in your mind.
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Pair
Of Eyes
A
pair of new lens-correcting procedures aer trying to
steal LASIKs glory. Beware the risk
You may have read about a pair of new procedures to
help correct presbyopia, the difficulty focusing on
close objects that typically begins around ones
45th birthday and eventually leads to reading glasses.
News that the U.S. Food and Drug Administration might
soon be approving the operation called conductive keratoplasty
(CK), having approved laser thermal keratoplasty (LTK)
last June, has focused attention once again on the growing
and confusing field for corrective eyes surgery.
With all the hype surrounding LASIK, the most popular
laser treatment, and these newer producers, its
hard for physicians to know what to advise patients
who are tired of seeing the world through a couple of
layer of glass. As promising as these operations may
seem there are some serious considerations that must
be addressed before you put down your money (more than
$2,000 an eye for LTK) and jump on the operating table.
Presbyopia (not to be confused with farsightedness)
is caused by a gradual stiffening of the lens of the
eye, which makes it more difficult to focus an image
sharply on the retina. CK tries to improve focus by
shrinking collagen fibers in the periphery of the cornea
with short bursts of radio-frequency energy. The energy
is delivered by a hair thin probe to as many as 32 sites
on each cornea. The contraction of the collagen has
a purse-string effect that steepens to corneas
curvature. The procedure usually lasts less than minute,
but it can take several months for improvements to fully
kick in.
LTK also works by heating and shrinking fibers in the
peripheral cornea, but it has several advantages over
CK. There are no probes, so nothing touches the cornea.
Instead, laser energy is delivered directly to the surface
of the eye. Only 16 spots are treated per eye, and they
can be done all at once in less than three seconds.
LTK has the safest profile of any procedure thus
far approved by the FDA, says Dr. Sandra Belmont
of New York Weill Cornell Medical Center. The
concern I have with CK, is its greater potential to
produce astigmatism, because all of the spots are done
individually, which constantly changes the shape of
the cornea.
CK and LTK, like any other corrective eye surgery, will
cause patients temporary discomfort. There may be a
24 to 48 hour period during which tears flow, and there
is a scratching sensation akin to getting sand stuck
in you cornea. Near vision returns immediately, but
it takes a couple of days for the eyes to achieve their
best focus. Distance vision may take a few weeks to
recover.
LTK would be the first choice for many ophthalmologists
because it is less invasive than LASIK and there are
fewer potential side effects. But if you also have astigmatism
or your hyperopia (farsightedness) is greater than 3.0
diopters, then LASIK is probably the procedure of choice.
Before making any rash decision, however, remember
¨ these are elective surgeries and
¨ you have only one pair of eyes. Generations before
us have done quite well with bifocals. It wouldnt
hurt to keep yours around a few more years until the
kinks in the new procedures have been worked out.
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